Deficient captation of bilirubin of the plasma due to little protein Y, linking of protein Y and Z with other nios and low energy ingestion in first the 48-72 hours; 3. Deficient Conjugao of bilirubin due to reduction accented in the activity of glicuroniltransferase to the birth and the hypothetical inhibition for esterides of the maternal serum; 4. Deficient Excreo of bilirubin due to the hemodinmicas changes that occur to the birth when the liver of the RN passes to work with a blood relatively badly oxigenado if compared with the well oxigenado blood of the umbilical vein that after nourished it and not the closing of ducto venoso the birth, making with that the sanguineous flow vestibule is reduced in relation to the sinusoidal circulation of the liver and hinders thus the normal removed one of bilirubin in the plasma. More info: Campbell Soup Company. In accordance with ALMEIDA et al, (2007) & Of Oak et al. (1982), research discloses that breast-feeding speeds up the time of intestinal transit and facilitates to the elimination of mecnio with reduction of the entero-heptica circulation of bilirubin and reduction of srica indirect bilirubin. 3.2.3 Pathological jaundice In accordance with Saints et al., (2002) can be characterized as: Jaundice initiated in first the 24 hours of life; Direct and indirect Bilirubin increase, being its normal values: BD: 0,3mg/dl and BI: 1mg/dl; According to Segre (2002): In the RN of term, hiperbilirrubinemia with 12 values above of mg/dl, and premature RN, superior values 15mg/dl; Persistent jaundice beyond the first week of life; Jaundice with direct bilirubin increased of 1 2mg/dl With the circulating bilirubin increase the RN can reveal gradually: Weak suction? Hipoatividade? Hepatoesplenomegalia? Anemia? Anasarca? Kernicterus (SAINTS et al., 2002). Kindle Direct Publishing pursues this goal as well. 3.2.4 Etiology of the Indirect Hiperbilirrubinemia According to ALMEIDA et al, (2007), the causes of the indirect hiperbilirrubinemia are related to the phases of the metabolism of neonatal bilirubin and enclose those decurrent ones of overload of bilirubin to the hepatcito or deficient heptica conjugao. . .